Vertaling van "the clearest clinical risk " (Nederlands → Frans) :

This project was set up following the observation that the clearest clinical risk factor involved in suicide is a previous attempted suicide.
La mise en place de ce projet part du constat que le facteur de risque clinique le plus clair concernant le suicide est la tentative de suicide.

With attempted suicides the clearest and most significant predictive risk factor for fatal suicidal behaviour, particular attention should be paid to providing adequate care and follow-up.
La tentative de suicide étant le facteur de risque du comportement suicidaire fatal le plus clair et le plus significatif en termes de prédiction, une attention toute particulière doit être portée à sa prise en charge et au suivi de celle-ci.

Acknowledgements: Voor haar waardevolle bijdrage in het gedeelte over meta-analyse: Cécile Dubois (KCE) Voor hun bijdrage bij het scoren van de indicatoren: Raf Brouns en Matthieu Rutgers (Belgian Stroke Council) Voor het valideren van de informatie over hun land: Zweden: Kiell Asplund (Chair, Risks Stroke Umeal), Bo Norrving (Professor, Lund University-Steering committee member Riks stroke) Nederland: Martien Limburg (Neuroloog, Flevoziekenhuis, Almere, Stichting Kennisnetwerk); Schotland: Martin Dennis (Division of Clinical Neurosciences – Western General Hospital University of Edinburgh), Peter Langhorne (Professor of Stroke Care, Cardiovascular and Medical Sciences Division – University of Glasgow) Verenigd Koninkrijk: Patrick Gompertz (Barts and the London Brain Attack Center, London), Gill Gluckie (Clinical lead, stroke, Guy’s and St. Thomas’ hospital, clinical lead, S/East London stroke network) Frankrijk: France Woimant (Service de neurologie, hôpital Lariboisière, Paris – “Agence Régionale de Santé – Ile-de-France”), Didier Leys (Département de neurologie, Hôpital universitaire de Lille) Duitsland: Peter Heuschmann (Neurologische klinik und poliklinik, Universitätsklinikum Würzburg) German Stroke Register Study Group), E. Bernd Ringelstein (Neurologische klinik und poliklinik, Universitätsklinikum Münster)
Remerciements : Pour son aide précieuse relative à la méta-analyse : Cécile Dubois (KCE) Pour leur contribution au scoring des indicateurs : Raf Brouns et Matthieu Rutgers (Belgian Stroke Council) Pour la validation de la description de leur pays : Suède : Kiell Asplund (Chair, Risks Stroke Umea), Bo Norrving (Professor, Lund University-Steering committee member Riks stroke) Pays-Bas : Martien Limburg (Neuroloog, Flevoziekenhuis, Almere, Stichting Kennisnetwerk) Ecosse : Martin Dennis (Division of Clinical Neurosciences – Western General Hospital University of Edinburgh), Peter Langhorne (Professor of Stroke Care, Cardiovascular and Medical Sciences Division – University of Glasgow) Grande-Bretagne : Patrick Gompertz (Barts and the London Brain Attack Center, London), Gill Gluckie (Clinical lead, stroke, Guy’s and St. Thomas’ hospital, clinical lead, S/East London stroke network) France : France Woimant (Service de neurologie, hôpital Lariboisière, Paris – “Agence Régionale de Santé – Ilede-France”), Didier Leys (Département de neurologie, Hôpital universitaire de Lille) Allemagne : Peter Heuschmann (Neurologische klinik und poliklinik, Universitätsklinikum Würzburg) German Stroke Register Study Group), E. Bernd Ringelstein (Neurologische klinik und poliklinik, Universitätsklinikum Münster)

This release contains forward-looking information about an agreement by Pfizer to acquire FoldRx, and about FoldRx’s product candidate tafamidis, its other clinical and preclinical development programs and its technology platform, including their potential benefits, that involves substantial risks and uncertainties. Such risks and uncertainties include, among other things, the satisfaction of conditions to closing the agreement; the uncertainties inherent in research and development; whether and when a new drug application for tafamidis will be filed with the FDA; decisions by regulatory authorities regarding whether and when to approve any drug applications that have been or may be filed for tafamidis and that may be filed for any other product candidates that may be generated by FoldRx’s technology platform as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of tafamidis and such other product candidates; and competitive developments. A further description of risks and uncertainties can be found in Pfizer’s Annual Report on Form 10-K for the fiscal year ended December 31, 2009 and in its reports on Form 10-Q and Form 8-K.
Such risks and uncertainties include, among other things, the satisfaction of conditions to closing the agreement; the uncertainties inherent in research and development; whether and when a new drug application for tafamidis will be filed with the FDA; decisions by regulatory authorities regarding whether and when to approve any drug applications that have been or may be filed for tafamidis and that may be filed for any other product candidates that may be generated by FoldRx’s technology platform as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of tafamidis and such other product candidates; and competitive developments.

Its clinical manifestations are looked upon as the final result of a negative spiral that sets in if the risk factors can no longer be counterbalanced by the protective factors that each individual possesses to a certain extent.
Ce qui se présente de façon clinique est considéré comme le résultat final d’une spirale négative qui s’installe si les facteurs de risque ne peuvent plus être contrebalancés par les facteurs de protection dont chacun dispose dans une certaine mesure.

Clinical risk management bestond vroeger als een managementniveau onder de andere bestuursniveaus.
Le clinical risk management consistait auparavant en un niveau de management parmi les autres niveaux de gestion.

How frequent is suicidal behaviour in the general population? What tendencies can be observed over time with respect to sociodemographic factors and clinical risk factors?
Quelle est l’occurrence du comportement suicidaire dans la population générale, quelles sont les tendances à travers le temps, au niveau des facteurs sociodémographiques et des facteurs de risques cliniques?

However, an increased risk of clinical failure with nasal treatment of multi-site MRSA colonisation has been associated with lowlevel resistance in one study 31 .
Cependant, un risque accru d'échec clinique dans le traitement nasal de la colonisation multi-site par MRSA a été associé, dans une étude 31 , à la résistance de faible niveau.

47. Van Damme H, Pierard L, Gillain D, Benoit T, Rigo P, Limet R. Cardiac risk assessment before vascular surgery: a prospective study comparing clinical evaluation, dobutamine stress echocardiography, and dobutamine Tc-99m sestamibi tomoscintigraphy.
49. Van Damme H, Pierard L, Gillain D, Benoit T, Rigo P, Limet R. Cardiac risk assessment before vascular surgery: a prospective study comparing clinical evaluation, dobutamine stress echocardiography, and dobutamine Tc-99m sestamibi tomoscintigraphy.

26. Eagle KA, Coley CM, Newell JB, Brewster DC, Darling RC, Strauss HW, et al. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery.
25. Eagle KA, Coley CM, Newell JB, Brewster DC, Darling RC, Strauss HW, et al. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery.