Traduction de «molecules as therapeutics targets » (Néerlandais → Français) :

Molecular and functional characterization of distinct tumor-associated macrophage (TAM) subsets and the evaluation of TAM-associated molecules as therapeutics targets
Determination of the involvement and contribution of mitochondrial uncoupling to epithelial-mesenchymal transition (EMT) and cancer stemness in the context of tumor metastasis

FoldRx is a development and discovery company focusing on first-in-class, disease-modifying, small molecule therapeutics to treat diseases of protein misfolding and aggregation (amyloidosis) based on the pioneer work of its scientific founders, Jeffery Kelly (The Scripps Research Institute) and Susan Lindquist (Whitehead Institute).
folding and its platform for drug and target discovery, the company is building a pipeline, initially for neurodegenerative and respiratory conditions. FoldRx’s pipeline includes a program in advanced clinical development to treat genetic neurologic and cardiovascular disorders, Transthyretin (TTR) Amyloid Polyneuropathy (ATTR-PN) and TTR Amyloid Cardiomyopathy (ATTR-CM), and a discovery program in cystic fibrosis, Parkinson’s, and Huntington’s disease based on its broad, proprietary, yeast-based drug discovery platform.