Traduction de «hmg-coa-reductase » (Néerlandais → Français) :

HMG-CoA reductase-inhibitoren Er is een verhoogd risico van myopathie bij gelijktijdige behandeling met bepaalde HMG-CoA reductase-inhibitoren (gemetaboliseerd door het cytochroom P450 3A4) en azoolantimycotica; in zeldzame gevallen resulteerde deze combinatie in rabdomyolyse met nierdisfunctie, secundair aan een myoglobinurie.
Inhibiteurs de l’HMG-CoA réductase Il existe un risque accru de myopathie lors d’un traitement combiné sous certains inhibiteurs de l’HMG-CoA réductase (métabolisés par le cytochrome P450 3A4) et antifongiques azolés ; dans de rares cas, cette association a provoqué une rhabdomyolyse avec dysfonction rénale, secondaire à une myoglobinurie.

C10AA HMG-CoA REDUCTASE - REMMERS (STATINES) 95.692.129 140.940.122 167.718.993 191.686.825 228.282.777 312.348.909 372.658.789 411.279.082 457.722.112 C10AB FIBRATEN 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 29.742.901 30.183.448 C10AC + C10AD + C10AX ANDERE HYPOLIPEMIERENDE MIDDELEN 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 4.640.263 6.334.594 Totaal 156.582.515 197.201.188 222.822.606 255.487.049 290.797.754 353.219.648 399.963.238 445.662.246 494.240.155
C10AA INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES) 95.692.129 140.940.122 167.718.993 191.686.825 228.282.777 312.348.909 372.658.789 411.279.082 457.722.112 C10AB FIBRATES 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 29.742.901 30.183.448 C10AC + C10AD + C10AX AUTRES HYPOLIPIDEMIANTS 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 4.640.263 6.334.594 Total 156.582.515 197.201.188 222.822.606 255.487.049 290.797.754 353.219.648 399.963.238 445.662.246 494.240.155

C10AA HMG-CoA REDUCTASE - REMMERS (STATINES) 89.390.441 107.786.574 112.875.154 136.558.641 193.189.140 231.591.803 260.221.489 294.475.605 347.553.667 C10AB FIBRATEN 61.808.427 61.066.153 68.900.770 67.894.445 44.066.362 26.918.242 33.126.411 33.692.996 34.432.427 C10AC + C10AD + C10AX + ANDERE HYPOLIPEMIERENDE MIDDELEN 482.238 455.728 425.595 416.998 1.128.836 3.788.724 5.612.784 7.864.901 11.900.081 C10BA Totaal 151.681.105 169.308.455 182.201.519 204.870.084 238.384.338 262.298.768 298.960.684 336.033.502 393.886.175
C10AA INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES) 89.390.441 107.786.574 112.875.154 136.558.641 193.189.140 231.591.803 260.221.489 294.475.605 347.553.667 C10AB FIBRATES 61.808.427 61.066.153 68.900.770 67.894.445 44.066.362 26.918.242 33.126.411 33.692.996 34.432.427 C10AC + C10AD + C10AX + C10BA AUTRES HYPOLIPIDEMIANTS 482.238 455.728 425.595 416.998 1.128.836 3.788.724 5.612.784 7.864.901 11.900.081

Inhibitoren van de HMG-CoA reductase (statines)
Inhibiteurs de la HMG-CoA réductase (statines)

Glivec kan de plasmaconcentratie verhogen van andere door CYP3A4 gemetaboliseerde geneesmiddelen (bv. triazolo-benzodiazepines, dihydropyridine calciumkanaal blokkers, bepaalde HMG-CoA reductase inhibitoren, nl. statines, enz.).
Par ailleurs, Glivec peut augmenter la concentration plasmatique d’autres médicaments métabolisés par le CYP3A4 (par exemple triazolo-benzodiazépines, inhibiteurs calciques de type dihydropyridine, certains inhibiteurs de l’HMG-CoA réductase, c’est à dire les statines, etc.).

ANDERE HYPOLIPEMIERENDE MIDDELEN FIBRATEN HMG-CoA REDUCTASE - REMMERS (STATINES)
INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES)

C10AA HMG-CoA REDUCTASE - REMMERS (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 372.658.546 464.861.301 C10AB FIBRATEN 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 33.123.513 C10AC + C10AD + C10AX ANDERE HYPOLIPEMIERENDE MIDDELEN 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 5.610.959 Totaal 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561 399.962.995 503.595.772
C10AA INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 372.658.546 464.861.301 C10AB FIBRATES 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 33.123.513 C10AC + C10AD + C10AX AUTRES HYPOLIPIDEMIANTS 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 5.610.959 Total 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561 399.962.995 503.595.772

FIBRATEN HMG-CoA REDUCTASE - REMMERS (STATINES)
AUTRES HYPOLIPIDEMIANTS FIBRATES INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES)

C10AA HMG-CoA REDUCTASE - REMMERS (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 C10AB FIBRATEN 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 C10AC + C10AD + C10AX ANDERE HYPOLIPEMIERENDE MIDDELEN 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 Totaal 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561
C10AA INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 C10AB FIBRATES 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 C10AC + C10AD + C10AX AUTRES HYPOLIPIDEMIANTS 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 Total 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561

C10AA HMG-CoA REDUCTASE - REMMERS (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 372.658.546 C10AB FIBRATEN 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 C10AC + C10AD + C10AX ANDERE HYPOLIPEMIERENDE MIDDELEN 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 Totaal 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561 399.962.995
C10AA INHIBITEURS DE LA HMG-CoA REDUCTASE (STATINES) 29.943.315 51.414.603 95.692.129 140.940.122 167.718.993 191.686.825 228.282.770 312.348.823 372.658.546 C10AB FIBRATES 66.106.101 66.301.254 60.437.420 55.863.051 54.738.487 63.449.200 62.170.278 40.046.220 24.223.503 C10AC + C10AD + C10AX AUTRES HYPOLIPIDEMIANTS 760.428 604.443 452.967 398.015 365.126 351.024 344.699 824.519 3.080.946 Total 96.809.844 118.320.300 156.582.515 197.201.188 222.822.606 255.487.049 290.797.747 353.219.561 399.962.995