Traduction de «higher doses showing increasing benefit » (Néerlandais → Français) :

Incremental benefits have been observed with indacaterol in escalating doses from 75 mcg up to 300 mcg, with higher doses showing increasing benefit for patients, particularly those with more severe disease.
Une augmentation du dosage de 75 mcg à 300 mcg s’est traduite par une progression des bénéfices pour les malades, les doses plus élevées profitant plus à ces derniers, en particulier, à ceux qui souffrent des formes plus sévères de la maladie.

There may be a small benefit from higher dosed patches than in lower dosed patches.
There was no difference in effect in trials where the dose was tapered or weaned off, compared to those where withdrawal was abrupt.