Vertaling van "for the most serious problems " (Nederlands → Frans) :

The most serious problems with antidepressants have to do with undertreatment and failing treatments, rather than overdoses.
Les problèmes les plus graves engendrés par les antidépresseurs sont le traitement non adéquat (undertreatment) et l’échec de traitement, plutôt que l’overdose liée à ces médicaments.

In case of treatment with drugs, patient compliance should be ensured, for the most serious problems caused by antidepressants are undertreatment and treatment failure.
En cas de traitement médicamenteux, on doit veiller à ce que le patient observe sa thérapie (compliance), car les problèmes les plus graves engendrés par les antidépresseurs sont le traitement non adéquat (undertreatment) et l’échec de traitement.

In view of the serious problems with the availability and effectiveness of MeSeA, FEDICT recommended, after examining the system, entrusting the application and infrastructure to an external partner who could solve the problems and extend the application with a portal for external partners.
In view of the serious problems with the availability and effectiveness of MeSeA, FEDICT recommended, after examining the system, entrusting the application and infrastructure to an external partner who could solve the problems and extend the application with a portal for external partners.

There is no doubt that suicide is the most serious complication of depression.
Le suicide constitue sans aucun doute la complication la plus grave de la dépression.

The easy accessibility of online help encourages young people to talk about very serious problems.
Ce seuil très bas de l’aide online fait que les jeunes osent aborder leurs problèmes très sérieux.

However, a fall in the number of RAS incidents originating in Belgium was recorded (30% instead of 47%) ●● The number of class 1 alerts (problems involving life-threatening risks or serious disturbances for the patient) and class 3 alerts (minor deficiencies) remained stable ●● For class 2 alerts (problems that can cause
However, a fall in the number of RAS incidents originating in Belgium was recorded (30% instead of 47%) ●● The number of class 1 alerts (problems involving life-threatening risks or serious disturbances for the patient) and class 3 alerts (minor deficiencies) remained stable ●● For class 2 alerts (problems that can cause

The seriousness of the situation, the differences in regulations from country to country, the difficulty of determining at the start of an incident whether it is a quality problem or a problem of pharmacovigilance, are factors which have to be taken into account.
The seriousness of the situation, the differences in regulations from country to country, the difficulty of determining at the start of an incident whether it is a quality problem or a problem of pharmacovigilance, are factors which have to be taken into account.

Yet for the person contemplating suicide, the problem is always a real one in the sense that he/she is seriously affected by it.
Pour la personne qui pense au suicide le problème est cependant toujours réel dans la mesure où elle le vit intensément.

A suicide is hardly ever a sudden or unpredictable event. Mostly, it is the end of a long and complex process in which the individuals concerned try, in vain, to find help and solutions to their problems.
Un suicide survient rarement de manière brutale, imprévisible; il est le plus souvent l’aboutissement d’un processus long et complexe au cours duquel l’individu essaie, en vain, de trouver aide et solutions.

The risk evaluation in case of pregnancy proved to be more difficult: it is true that most of the epidemiological studies available at the time led to the conclusion that a total caffeine intake of less than 300 mg/day does not constitute a problem.
L’évaluation du risque par rapport à la grossesse leur a paru plus difficile: la plupart des études épidémiologiques disponibles à cette époque les ont amené à penser qu’un apport global en caféine inférieur à 300 mg/jour ne pose pas de problème mais la question des effets possibles sur la descendance d’un apport supérieur à cette valeur restait toutefois sans réponse.