Traduction de «assumptions and sensitivity analysis » (Néerlandais → Français) :

Key assumptions and sensitivity analysis information are provided in note 10 to the Group’s consolidated financial statements in the 2008 Annual Report.
Des informations sur les hypothèses-clés et l’analyse de sensibilité sont fournies dans l’annexe 10 des comptes consolidés du Groupe figurant dans le Rapport annuel 2008.

Spontaneous cessation rate: 2.5% OR counselling only: 1.73 Incremental OR NRT gum (relative to counselling only): 1.63 Incremental OR NRT patch (relative to counselling only): 1.79 Incremental OR NRT spray (relative to counselling only): 2.35 Incremental OR NRT inhaler (relative to counselling only): 2.14 Incremental OR bupropion (relative to counselling only): 2.30 % of smokers still under treatment after the first month: 50% (range 40-60% in sensitivity analysis) % of smokers still under treatment after the second month: 20% (range 15-25% in sensitivity analysis) Lifetime relapse probability after one year of abstinence: 35% (range 10-50% in sensitivity analysis) Effect of smoking cessation on mortality derived from the results of the American Cancer Society Prevention Study II. The mortality rate for former smokers was projected by calculating a weighted average of the incremental differentials between mortality rates of neversmokers and smokers, weighted according to the duration of abstinence.
Spontaneous cessation rate: 2.5% OR counselling only: 1.73 Incremental OR NRT gum (relative to counselling only): 1.63 Incremental OR NRT patch (relative to counselling only): 1.79 Incremental OR NRT spray (relative to counselling only): 2.35 Incremental OR NRT inhaler (relative to counselling only): 2.14 Incremental OR Buproprion (relative to counselling only): 2.30 % of smokers still under treatment after the first month: 50% (range 40-60% in sensitivity analysis) % of smokers still under treatment after the second month: 20% (range 15-25% in sensitivity analysis) Lifetime relapse probability after one year of abstinence: 35% (range 10-50% in sensitivity analysis) Effect of smoking cessation on mortality derived from the results of the American Cancer Society Prevention Study II. The mortality rate for former smokers was projected by calculating a weighted average of the incremental differentials between mortality rates of neversmokers and smokers, weighted according to the duration of abstinence.

2001 € Costs include additional time spent by GP offering, prescribing and following-up pharmacological treatment and retail prices of NRT or bupropion GP counselling occurs opportunistically during consultations for other diseases Counselling takes 10 minutes (range 5-15 minutes in sensitivity analysis).
2001 € Costs include additional time spent by GP offering, prescribing and following-up pharmacological treatment and retail prices of NRT or Buproprion GP counselling occurs opportunistically during consultations for other diseases Counselling takes 10 minutes (range 5-15 minutes in sensitivity analysis).

Treatment (both NRT and bupropion) lasts at least 1 month Retail price of NRT gum: not reported Retail price of NRT patch (3-month course): €354.54 (€, 2001) Retail price of NRT nasal spray (3-months course): €743.02 3% (range 0-5% in sensitivity analysis)
Treatment (both NRT and Buproprion) lasts at least 1 month Retail price of NRT gum: not reported Retail price of NRT patch (3-month course): €354.54 (€, 2001) Retail price of NRT nasal spray (3-months course): €743.02 3% (range 0-5% in sensitivity analysis)

Kim C et al - Am.Heart J. 44 2001 meta analysis yes 82 studies Coronary disease diagnostic : maximum sensitivity with vasodilatator combined with SPECT, maximum specificity with vasodilatator combined with DSE.
Kim C et al - Am.Heart J. 46 2001 meta analysis yes 82 studies Coronary disease diagnostic : maximum sensitivity with vasodilatator combined with SPECT, maximum specificity with vasodilatator combined with DSE.